Ekholm E M, Piha S J, Antila K J, Erkkola R U
Department of Obstetrics and Gynaecology, Turku University, Finland.
Br J Obstet Gynaecol. 1993 Feb;100(2):177-82. doi: 10.1111/j.1471-0528.1993.tb15217.x.
To study the physiological responses to noninvasive cardiovascular autonomic function tests in normal pregnancy.
Cardiovascular autonomic responses in 60 women at 22 to 29 weeks gestation and 62 nonpregnant women were investigated using the Valsalva manoeuvre as well as orthostatic, quiet breathing, deep breathing, and isometric handgrip tests.
Compared with nonpregnant women, those who were pregnant showed significantly lower heart rate variability during normal breathing and a blunted tachycardic reaction to blowing during the Valsalva manoeuvre. The vagally controlled biphasic heart rate response to standing was also attenuated in the pregnant group.
The cardiovascular responses were blunted in mid-pregnancy indicating a decrease in parasympathetic cardiovascular control.
研究正常妊娠期间对无创心血管自主神经功能测试的生理反应。
采用瓦尔萨尔瓦动作以及直立位、安静呼吸、深呼吸和等长握力测试,对60名妊娠22至29周的女性和62名未怀孕女性的心血管自主神经反应进行了研究。
与未怀孕女性相比,怀孕女性在正常呼吸时心率变异性显著降低,在瓦尔萨尔瓦动作期间对吹气的心动过速反应减弱。怀孕组对站立的迷走神经控制的双相心率反应也减弱。
妊娠中期心血管反应减弱,表明副交感神经对心血管的控制减少。