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标准开放性阑尾切除术和胆囊切除术后小肠梗阻的术后发病率:耶鲁-纽黑文医院的一项为期六年的回顾性队列研究。

The postoperative incidence of small bowel obstruction following standard, open appendectomy and cholecystectomy: a six-year retrospective cohort study at Yale-New Haven Hospital.

作者信息

Zbar R I, Crede W B, McKhann C F, Jekel J F

机构信息

Department of Surgery, Yale University School of Medicine, New Haven.

出版信息

Conn Med. 1993 Mar;57(3):123-7.

PMID:8477590
Abstract

The incidence of postoperative small bowel obstruction (SBO) after standard, open appendectomy and cholecystectomy was calculated during a six-year period at a university medical center hospital, which is the larger of two local, community hospitals. A cohort of 567 patients who underwent either a standard, open appendectomy or cholecystectomy from 1 October 1985 through 30 September 1986 was assembled. Of these patients, 182 (32.1%) were readmitted to the hospital prior to 1 October 1991 and thereby received follow-up. The time-related incidence of readmission to the hospital with a specific diagnosis of SBO as estimated by the Kaplan-Meier method was tabulated. This analysis revealed the following incidence rates of postoperative SBO: 10.7% following appendectomy during 64 months of follow-up (n = 41) and 6.4% following cholecystectomy during 67 months (n = 141). The Kaplan-Meier product-limit incidence of postoperative SBO was significantly different for standard appendectomy versus standard cholecystectomy (Breslow-Cox P value < 0.0277). This implies that the anatomical position and/or the likelihood of perioperative infection associated with open, abdominal surgery plays a significant role in subsequent adhesion formation and development of SBO. These data may be compared to laparoscopic techniques in future studies.

摘要

在一所大学医学中心医院(当地两家社区医院中较大的一家),计算了标准开放式阑尾切除术和胆囊切除术后小肠梗阻(SBO)的发生率,为期六年。选取了1985年10月1日至1986年9月30日期间接受标准开放式阑尾切除术或胆囊切除术的567例患者组成队列。在这些患者中,182例(32.1%)在1991年10月1日前再次入院,从而获得随访。通过Kaplan-Meier法估计的因特定诊断为SBO而再次入院的时间相关发生率被制成表格。该分析揭示了术后SBO的以下发生率:阑尾切除术后64个月的发生率为10.7%(n = 41),胆囊切除术后67个月的发生率为6.4%(n = 141)。标准阑尾切除术与标准胆囊切除术的术后SBO的Kaplan-Meier乘积限发生率有显著差异(Breslow-Cox P值< 0.0277)。这意味着与开放式腹部手术相关的解剖位置和/或围手术期感染的可能性在随后粘连形成和SBO发展中起重要作用。这些数据可在未来研究中与腹腔镜技术进行比较。

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