Arolt V, Steege D, Nolte A
Klinik für Psychiatrie, Medizinischen Universität zu Lübeck.
Fortschr Neurol Psychiatr. 1993 Mar;61(3):90-105. doi: 10.1055/s-2007-999080.
Disorders of smooth pursuit eye movements and saccadic eye movements have been reported frequently in schizophrenics. Probably 50% of the schizophrenic probands and of their unaffected relatives perform abnormal smooth pursuit movements. These deficiencies have been regarded as a possible genetic trait marker for schizophrenic vulnerability. Saccadic eye movements have been investigated less intesively. The most prominent pathological feature is a lack of precision of reflexive saccades in case of schizophrenic probands. Although a large body of research has been conducted, the multitude of the results of eye movement disorders in schizophrenics and also technical and methodological problems impair the significance of these findings. In this review, the most important results are critically elaborated and research perspectives are pointed out. A valid identification of eye movement abnormalities is necessary.
精神分裂症患者中经常出现平稳跟踪眼球运动和扫视眼球运动障碍。大概50%的精神分裂症先证者及其未患病的亲属存在异常的平稳跟踪运动。这些缺陷被认为是精神分裂症易感性的一种可能的遗传特征标记。对扫视眼球运动的研究较少。精神分裂症先证者最突出的病理特征是反射性扫视缺乏精确性。尽管已经进行了大量研究,但精神分裂症患者眼球运动障碍的众多结果以及技术和方法上的问题削弱了这些发现的重要性。在这篇综述中,对最重要的结果进行了批判性阐述,并指出了研究前景。对眼球运动异常进行有效识别是必要的。