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A血型和I抗原位点在人红细胞膜内翻小泡和外翻小泡上的定位

Localization of blood-group A and I antigenic sites on inside-out and rightside-out human erythrocyte membrane vesicles.

作者信息

Schenkel-Brunner H, Cartron J P, Doinel C

出版信息

Immunology. 1979 Jan;36(1):33-6.

Abstract

Investigations of the fixation of 125I-labelled anti-A and anti-I antibodies onto rightside-out and inside-out membrane vesicles prepared from human A1 and OI erythrocytes, respectively, showed that both antibodies were bound to the rightside-out vesicles, giving clear evidence that blood group A and I antigenic sites are exclusively localized on the external surface of the membrane.

摘要

分别对由人A1和OI红细胞制备的外翻和内翻膜囊泡进行125I标记的抗A和抗I抗体固定化研究,结果表明两种抗体均与外翻囊泡结合,明确证明血型A和I抗原位点仅位于膜的外表面。

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