Tanaka A, Yamagishi T, Satou T, Yorifuji H, Fukutake K, Fujimaki M
Department of clinical pathology, Tokyo Medical College.
Rinsho Ketsueki. 1993 Mar;34(3):294-300.
The clinical courses of 9 patients with acquired immunodeficiency syndrome (AIDS) complicated by pneumocystis carinii pneumonia (PCP) were followed to investigate the clinical significance of the measurement of various parameters such as serum lactate dehydrogenase (LDH). The mean duration of symptoms before diagnosis was 20 days, and the median duration of therapy was 29.5 days. Serum LDH activity increased in 8 of 9 cases. The isozyme pattern in all cases was characterized by high LDH3 values from the early stage. However, inflammatory markers did not increase in most cases. There were good correlations between the levels of LDH, clinical course, and PaO2.
对9例获得性免疫缺陷综合征（AIDS）合并卡氏肺孢子虫肺炎（PCP）患者的临床病程进行了跟踪，以研究血清乳酸脱氢酶（LDH）等各种参数测量的临床意义。诊断前症状的平均持续时间为20天，治疗的中位持续时间为29.5天。9例中有8例血清LDH活性升高。所有病例的同工酶模式从早期开始就以LDH3值高为特征。然而，大多数病例中的炎症标志物并未升高。LDH水平、临床病程和动脉血氧分压（PaO2）之间存在良好的相关性。
