Mikos B, Bíró E
Borsod-A. -Z. Megyei Kórház, Gyermekegészségügyi Központ-OTE II. Gyermekgyógyászati Tanszék, Miskolc.
Orv Hetil. 1993 Apr 25;134(17):907-10.
The clinical course of eight patients with Amanita phalloides poisoning is reviewed. Early diagnosis was based on the history, characteristic clinical features and non-specific laboratory data. A complex supportive therapy with gastric lavage, bowel irrigation, correction of volume and electrolyte abnormalities, and penicillin-G (Penicillin, Biogal), silibinin (Legalon SIL, Madaus), thioctacid (Thioctacid, Asta), corticosteroid (Di-Adreson-F aquosum, Organon) administration was commenced in every cases before identification of the mushroom. Haemoperfusion was performed in six cases, and in one patient plasmapheresis was applied as well. Seven children recovered completely. Unfortunately, a girl of 12 years died. According to the authors' experience, the use of non-invasive and invasive methods of the non-specific detoxication is proposed in case of severe Amanita phalloides poisoning.
回顾了8例毒鹅膏中毒患者的临床病程。早期诊断基于病史、特征性临床特征及非特异性实验室数据。在未识别出蘑菇之前，每例患者均开始采用包括洗胃、肠道灌洗、纠正容量和电解质异常以及使用青霉素G（青霉素，Biogal）、水飞蓟宾（利加隆SIL，马道斯）、硫辛酸（硫辛酸，阿斯塔）、皮质类固醇（地塞米松磷酸钠水溶液，欧加农）的综合支持疗法。6例患者进行了血液灌流，1例患者还进行了血浆置换。7名儿童完全康复。不幸的是，一名12岁女孩死亡。根据作者的经验，对于严重的毒鹅膏中毒，建议采用非特异性解毒的非侵入性和侵入性方法。
