[Amanita phalloides poisoning in a 15-year case load of a pediatric intensive care unit].

The clinical course of eight patients with Amanita phalloides poisoning is reviewed. Early diagnosis was based on the history, characteristic clinical features and non-specific laboratory data. A complex supportive therapy with gastric lavage, bowel irrigation, correction of volume and electrolyte abnormalities, and penicillin-G (Penicillin, Biogal), silibinin (Legalon SIL, Madaus), thioctacid (Thioctacid, Asta), corticosteroid (Di-Adreson-F aquosum, Organon) administration was commenced in every cases before identification of the mushroom. Haemoperfusion was performed in six cases, and in one patient plasmapheresis was applied as well. Seven children recovered completely. Unfortunately, a girl of 12 years died. According to the authors' experience, the use of non-invasive and invasive methods of the non-specific detoxication is proposed in case of severe Amanita phalloides poisoning.