Somogyi L, Cikes N, Marusić M
Department of Physiology, School of Medicine, Zagreb, Croatia.
Scand J Rheumatol. 1993;22(2):58-62. doi: 10.3109/03009749309095116.
The American Rheumatism Association (ACR) preliminary and revised criteria for classification of systemic lupus erythematosus (SLE) were evaluated for sensitivity and specificity in a population of 100 patients with SLE and 100 patients with other rheumatic diseases. Bayes' theorem was applied for evaluation of ARA criteria for the classification of SLE and a scoring system was developed which allows simple determination of the probability of SLE. The evaluation revealed considerable differences in values of the ARA criteria. The serologic tests and discoid lupus appeared to be the most distinctive criteria, while Raynaud's phenomenon, oral and nasal ulcers and arthritis were of little value. Comparison of SLE and control patients presenting the same number of criteria revealed that patients with SLE exhibit more distinctive criteria. This finding emphasizes the need for a quantitative evaluation of classification criteria.
对美国风湿病协会（ACR）系统性红斑狼疮（SLE）分类的初步及修订标准，在100例SLE患者和100例其他风湿性疾病患者群体中进行了敏感性和特异性评估。应用贝叶斯定理评估ARA标准对SLE的分类情况，并开发了一个评分系统，该系统能简单地确定SLE的概率。评估显示ARA标准的值存在显著差异。血清学检查和盘状狼疮似乎是最具特异性的标准，而雷诺现象、口腔和鼻溃疡以及关节炎的价值不大。对具有相同标准数量的SLE患者和对照患者进行比较发现，SLE患者表现出更具特异性的标准。这一发现强调了对分类标准进行定量评估的必要性。
