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Efficacy of the somatostatin analog octreotide in the treatment of two patients with refractory diabetic diarrhea.

作者信息

Walker J J, Kaplan D S

机构信息

Department of Medicine, University Hospital, State University of New York Health Science Center, Syracuse.

出版信息

Am J Gastroenterol. 1993 May;88(5):765-7.

PMID:8480746
Abstract

Two patients with severe refractory diabetes-related diarrhea are described. One patient had steatorrhea. Both responded to octreotide during a mean follow-up period of 7 months. The pathophysiology of diabetic diarrhea and the potential mechanism of action of octreotide are discussed. The only adverse side effect reported was hypoglycemia in one of the patients, which required a reduction of the insulin dose. Octreotide is a safe and effective agent for the treatment of refractory diabetic diarrhea.

摘要

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