Bakheet S, Hammami M M
Department of Radiology, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Clin Nucl Med. 1993 Apr;18(4):307-12. doi: 10.1097/00003072-199304000-00008.
In patients with differentiated thyroid cancer, radioiodine uptake in the area of the lung usually denotes metastasis; however, it could represent an uptake by unrelated pulmonary disease or by the breasts, or external contamination. In this study, 22 foci that simulated lung metastasis on 11 thyroid and whole body scans were proven not to be metastasis by reimaging after cleaning (15 foci), or were strongly suspected to be due to external contamination because of the features of other images (7 foci). All foci were noted only on anterior views of the chest. Of the 22 foci, 19 were focal, two were smeared, and one was lobar. Foci were multiple in 7 scans, unilateral in 10 scans, and were associated with other artifacts in 4 scans. Caution should be used in interpreting apparent pulmonary radioiodine uptake as lung metastasis; reimaging after cleaning the skin and changing garment should be obtained when the uptake is confined to anterior views of the chest and/or when its pattern is atypical.
在分化型甲状腺癌患者中，肺部区域的放射性碘摄取通常提示转移；然而，它可能代表由无关的肺部疾病、乳房摄取或外部污染所致。在本研究中，11例甲状腺及全身扫描显示模拟肺转移的22个病灶，经清洗后再次成像证实其中15个病灶并非转移灶，或因其他影像特征而强烈怀疑7个病灶是由外部污染所致。所有病灶仅在胸部前位像上被发现。22个病灶中，19个为局灶性，2个为涂抹状，1个为大叶性。7次扫描病灶为多发，10次扫描病灶为单侧，4次扫描病灶伴有其他伪影。将明显的肺部放射性碘摄取解读为肺转移时应谨慎；当摄取局限于胸部前位像和/或其形态不典型时，应在清洁皮肤和更换衣物后再次成像。
