Stephan R, Bulling E, Steinbeck A
Zentralbl Bakteriol Orig A. 1977;237(2-3):254-63.
2713 salmonella strains having been isolated by veterinary laboratories in the Federal Republic of Germany including West Berlin in 1974 were tested for resistance to tetracyclines, ampicillin, chloramphenicol, kanamycin, gentamycin, furazolidone, nitrofurazone, and trimethoprim. 21.7% of the strains tested were resistant to one or several of the antibacterially effective substances examined. The proportion of the resistant strains amounted to 52% for S. typhimurium and 4.7% for S. typhimurium var. copenhagen, 16.8% for S. enteritidis, and 22.1% for S. panama, 85.1% of all resistant strains belonged to these types. Out of 589 resistant strains found, resistance determinants were present in 93.7% to tetracyclines, 34.6% to ampicillin, 32.4% to chloramphenicol, 25.3% to kanamycin, 3.4% to furazolidone, and 0.5% to nitrofurazone. 1 strain of S. typhimurium var. copenhagen had a transmissible determinant of resistance to trimethoprim. No strain was resistant to gentamycin. 93.4% of the strains transmitted resistance determinants to E. coli K-12. A transmission of resisance to furazolidone and nitrofurazone could not be demonstrated. The serotypes were exhibiting clear-cut differences in their resistances patterns.
1974年,德意志联邦共和国(包括西柏林)的兽医实验室分离出2713株沙门氏菌菌株,对其进行了四环素、氨苄青霉素、氯霉素、卡那霉素、庆大霉素、呋喃唑酮、呋喃西林和甲氧苄啶耐药性检测。所检测菌株中有21.7%对一种或几种所检测的抗菌有效物质耐药。鼠伤寒沙门氏菌的耐药菌株比例为52%,哥本哈根鼠伤寒沙门氏菌变种为4.7%,肠炎沙门氏菌为16.8%,巴拿马沙门氏菌为22.1%,所有耐药菌株中有85.1%属于这些类型。在所发现的589株耐药菌株中,93.7%存在对四环素的耐药决定簇,34.6%对氨苄青霉素耐药,32.4%对氯霉素耐药,25.3%对卡那霉素耐药,3.4%对呋喃唑酮耐药,0.5%对呋喃西林耐药。1株哥本哈根鼠伤寒沙门氏菌变种有对甲氧苄啶的可传递耐药决定簇。没有菌株对庆大霉素耐药。93.4%的菌株将耐药决定簇传递给大肠杆菌K - 12。未证实对呋喃唑酮和呋喃西林的耐药性传递。各血清型在其耐药模式上表现出明显差异。