Mashako M N, Luki N, Nsibu N, Kapongo N, Bankoto M, Mupuala M, Bitumba M, Muyembe T L
Département de pédiatrie, cliniques universitaires, Kinshasa, République du Zaïre.
Pediatrie. 1991;46(10):691-6.
292 Salmonella strains were isolated between 1986-1988 in the bacteriological unit of the Cliniques Universitaires de Kinshasa (Zaïre). One hundred of these strains were isolated from pediatric samples. The most frequent strains were S typhi, S enteritidis and S typhimurium. S typhi strains were sensitive to all antibiotics tested. The other salmonella serotypes had an increasing resistance to several antibiotics especially ampicillin, streptomycin, tetracyclin and kanamycin. A significant decline was observed with chloramphenicol and sulfamethoxazol-trimetoprim. Stool-isolated strains from children were found to be resistant to all antibiotics in common use in 5/6 cases. In systemic Salmonella infection, treatment with chloramphenicol or sulfamethoxazole-trimetoprim plus gentamycin is probably preferable to any other antibiotic recommended for Salmonella infection.
1986年至1988年间,在金沙萨大学诊所(扎伊尔)的细菌学部门分离出292株沙门氏菌菌株。其中100株菌株是从儿科样本中分离出来的。最常见的菌株是伤寒沙门氏菌、肠炎沙门氏菌和鼠伤寒沙门氏菌。伤寒沙门氏菌菌株对所有测试抗生素敏感。其他沙门氏菌血清型对几种抗生素的耐药性不断增加,尤其是氨苄青霉素、链霉素、四环素和卡那霉素。氯霉素和磺胺甲恶唑-甲氧苄啶的耐药性显著下降。在5/6的病例中,从儿童粪便中分离出的菌株对所有常用抗生素均耐药。在全身性沙门氏菌感染中,用氯霉素或磺胺甲恶唑-甲氧苄啶加庆大霉素治疗可能比推荐用于沙门氏菌感染的任何其他抗生素更可取。