丝状病毒的VP35和VP40蛋白。马尔堡病毒与埃博拉病毒之间的同源性。

The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses.

作者信息

Bukreyev A A, Volchkov V E, Blinov V M, Netesov S V

机构信息

Institute of Molecular Biology, Koltsovo, Novosibirsk Region, Russian Federation.

出版信息

FEBS Lett. 1993 May 3;322(1):41-6. doi: 10.1016/0014-5793(93)81107-b.

DOI:10.1016/0014-5793(93)81107-b

PMID:8482365

Abstract

The fragments of genomic RNA sequences of Marburg (MBG) and Ebola (EBO) viruses are reported. These fragments were found to encode the VP35 and VP40 proteins. The canonic sequences were revealed before and after each open reading frame. It is suggested that these sequences are mRNA extremities and at the same time the regulatory elements for mRNA transcription. Homology between the MBG and EBO proteins was discovered.

摘要

报道了马尔堡病毒（MBG）和埃博拉病毒（EBO）的基因组RNA序列片段。发现这些片段编码VP35和VP40蛋白。在每个开放阅读框前后揭示了规范序列。提示这些序列是mRNA末端，同时也是mRNA转录的调控元件。发现了MBG和EBO蛋白之间的同源性。