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Adenine dinucleotide-mediated cytosolic free Ca2+ oscillations in single hepatocytes.

作者信息

Green A K, Dixon C J, McLennan A G, Cobbold P H, Fisher M J

机构信息

Department of Human Anatomy and Cell Biology, University of Liverpool, UK.

出版信息

FEBS Lett. 1993 May 10;322(2):197-200. doi: 10.1016/0014-5793(93)81567-j.

Abstract

Single rat hepatocytes microinjected with aequorin respond to Ca(2+)-mobilizing agonists, including ADP and ATP, with oscillations in cytosolic free Ca2+. We show here that single rat hepatocytes also respond to the adenine dinucleotides Ap3A and Ap4A with Ca2+ oscillations which resemble those induced by ADP and ATP.

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