Some immunological aspects on human Schistosoma mansoni infection in Egypt.

Human Schistosomiasis mansoni is a chronic disease, which ranges from subclinical infection to huge hepatosplenomegaly. Reducing the risk of infection remains the aim of many control measures. So the present study was designed to evaluate the interaction between S. mansoni infection and immunological system of the host. The study included 3 groups of 50 adult males each. The first group was control group, the second group was early S. mansoni infection and third group was advanced schistosomiasis with hepatosplenomegaly. The results showed some changes in both humoral and cellular immune response during the course of infection.