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埃及曼氏血吸虫感染的一些免疫学方面

Some immunological aspects on human Schistosoma mansoni infection in Egypt.

作者信息

el Marsafy A, el Okbi S M, el Adawy N

机构信息

Department of Immuno-allergy, Ministry of Health Education Hospitals, Cairo.

出版信息

J Egypt Soc Parasitol. 1993 Apr;23(1):179-87.

PMID:8482864
Abstract

Human Schistosomiasis mansoni is a chronic disease, which ranges from subclinical infection to huge hepatosplenomegaly. Reducing the risk of infection remains the aim of many control measures. So the present study was designed to evaluate the interaction between S. mansoni infection and immunological system of the host. The study included 3 groups of 50 adult males each. The first group was control group, the second group was early S. mansoni infection and third group was advanced schistosomiasis with hepatosplenomegaly. The results showed some changes in both humoral and cellular immune response during the course of infection.

摘要

人类曼氏血吸虫病是一种慢性疾病,范围从亚临床感染到巨大的肝脾肿大。降低感染风险仍然是许多控制措施的目标。因此,本研究旨在评估曼氏血吸虫感染与宿主免疫系统之间的相互作用。该研究包括3组,每组50名成年男性。第一组为对照组,第二组为曼氏血吸虫早期感染组,第三组为伴有肝脾肿大的晚期血吸虫病组。结果显示,在感染过程中,体液免疫和细胞免疫反应均发生了一些变化。

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