The effect of nifedipine [correction of nifidipine] and cimetidine on the haemodynamics of Egyptian bilharzial pulmonary hypertension.

The pathogenesis of bilharzial pulmonary hypertension differs from the hypoxic type of pulmonary hypertension. Nifedipine [corrected] a calcium channel blocker was tried as a treatment for lowering pulmonary artery pressure. Nifedipine [corrected] 20 mg sublingually was found to lower the pulmonary artery pressure but not to a statistically significant level. No significant changes before and after 200 mg cimetidine intravenous, were seen.