蟾蜍科蟾蜍（黑蟾蜍属）中的生物碱：十氢喹啉、 pumiliotoxins和高pumiliotoxins、吲哚里西啶、吡咯里西啶和喹诺里西啶。
Alkaloids from bufonid toads (Melanophryniscus): decahydroquinolines, pumiliotoxins and homopumiliotoxins, indolizidines, pyrrolizidines, and quinolizidines.
作者信息
Garraffo H M, Spande T F, Daly J W, Baldessari A, Gros E G
机构信息
Laboratory of Bioorganic Chemistry, NIDDK, NIH, Bethesda, MD 20892.
出版信息
J Nat Prod. 1993 Mar;56(3):357-73. doi: 10.1021/np50093a008.
PMID:8482947
Abstract
Skins of bufonid toads of the genus Melanophryniscus contain several classes of alkaloids: decahydroquinolines, pumiliotoxins, allopumiliotoxins, homopumiliotoxins, both 3,5- and 5,8-disubstituted indolizidines, 3,5-disubstituted pyrrolizidines, and a 1,4-disubstituted quinolizidine. Tricyclic alkaloids, including precoccinelline [193A] and alkaloid 236, an oxime methyl ether, are present in one population of Melanophryniscus stelzneri.
摘要
黑蟾属的蟾蜍皮肤含有几类生物碱
十氢喹啉、蟾蜍毒素、别蟾蜍毒素、高蟾蜍毒素、3,5-二取代和5,8-二取代的吲哚嗪、3,5-二取代的吡咯嗪以及1,4-二取代的喹嗪。三环生物碱，包括前瓢虫碱[193A]和一种肟甲基醚生物碱236，存在于斯氏黑蟾的一个种群中。
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