Seicshnaydre M A, Frable M A
Department of Otolaryngology-Head and Neck Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond.
Otolaryngol Head Neck Surg. 1993 Apr;108(4):344-7. doi: 10.1177/019459989310800406.
Kawasaki disease is an acute febrile illness of unknown etiology that occurs primarily in childhood. Early diagnosis and treatment can reduce the risk of cardiac complications of Kawasaki disease, which carries a 1% to 2% mortality for cardiovascular events. Clinical features include: (1) fever; (2) conjunctival injection; (3) oral cavity changes; (4) changes in the peripheral extremities; (5) erythematous rash; and (6) cervical adenopathy without suppuration. We describe three cases in detail and survey a series of 42 patients at our institution. Otolaryngologic manifestations were found to occur in the early stages of Kawasaki disease. The otolaryngologist may see these patients early in the disease and should be alert to the signs and symptoms for appropriate diagnosis and treatment. Characteristics of Kawasaki disease, difficulties in diagnosis during the initial febrile stage, and the importance of early diagnosis by the otolaryngologist is stressed.
川崎病是一种病因不明的急性发热性疾病，主要发生于儿童期。早期诊断和治疗可降低川崎病心脏并发症的风险，其心血管事件死亡率为1%至2%。临床特征包括：（1）发热；（2）结膜充血；（3）口腔改变；（4）四肢末端变化；（5）红斑皮疹；（6）颈部非化脓性淋巴结肿大。我们详细描述了3例病例，并对我院的42例患者进行了系列调查。发现川崎病早期会出现耳鼻喉科表现。耳鼻喉科医生可能在疾病早期就会接诊这些患者，应警惕相关体征和症状以便进行恰当的诊断和治疗。强调了川崎病的特征、发热初期诊断的困难以及耳鼻喉科医生早期诊断的重要性。
