Knirel' Iu A, Kochetkov N K
Biokhimiia. 1993 Feb;58(2):182-201.
The review summarizes the data on the core structure of bacterial lipopolysaccharides (LPS) which represents an oligosaccharide binding the lipid moiety of the macromolecule to the O-antigenic polysaccharide chain. Both S-strains with complete LPS and R-mutants having various defects of the core biosynthesis are considered. The role of the core in the outer membrane functioning and manifestation of antigenic specificity of LPS is discussed.
该综述总结了关于细菌脂多糖(LPS)核心结构的数据,LPS的核心结构是一种将大分子的脂质部分与O抗原多糖链结合的寡糖。文中考虑了具有完整LPS的S菌株以及核心生物合成存在各种缺陷的R突变体。讨论了核心在外膜功能以及LPS抗原特异性表现中的作用。