Hudson N, Wilkinson M J, Swannell A J, Steele R J, Hawkey C J
Department of Therapeutics, University Hospital, Queen's Medical Centre, Nottingham, UK.
Aliment Pharmacol Ther. 1993 Apr;7(2):197-200. doi: 10.1111/j.1365-2036.1993.tb00090.x.
A 38-year-old man with seropositive arthropathy on long-standing treatment with diclofenac slow release presented with abdominal pain, diarrhoea and anaemia. Upper gastrointestinal endoscopy and barium series were unremarkable. Five months later he presented with a right iliac fossa mass. Investigations revealed discrete ulceration in the terminal ileum and caecum confirmed at laparotomy. Other possible causes of intestinal ulceration were excluded suggesting a diagnosis of non-steroidal anti-inflammatory drug associated intestinal ulceration.
一名38岁男性，长期服用双氯芬酸缓释片治疗血清反应阳性的关节病，出现腹痛、腹泻和贫血症状。上消化道内镜检查和钡剂造影均无异常。五个月后，他出现右下腹包块。检查发现回肠末端和盲肠有散在溃疡，剖腹手术得以证实。排除了其他可能导致肠道溃疡的原因，提示诊断为非甾体抗炎药相关性肠道溃疡。
