Elamin E A, Mohamed G E, Fadl M, Elias S, Saleem M S, Elbashir M O
Department of Parasitology, Faculty of Veterinary Science, University of Khartoum, Sudan.
Br Vet J. 1993 Mar-Apr;149(2):195-200. doi: 10.1016/S0007-1935(05)80089-2.
Sheathed microfilariae (mean length 278 +/- 10 microns SEM; mean width 7.2 +/- 0.8 microns) were detected in the blood of 7/14 housed camels (Camelus dromedarius). Microfilaraemic camels of either sex were inappetent, lethargic, reluctant to move and exhibited weakness in the hind limbs; some remained in sternal recumbency. Cardiac disorders, orchitis and skin nodules were conspicuously absent. The microfilariae showed a biphasic pattern in the blood that peaked at 20:00 and plateaued between 04:00 and 06:00. Adult filarial worms were recovered from the mesenteric and femoral arteries. Marked clinical improvement within 1-2 weeks was seen in three camels treated at 10:00 with a single subcutaneous injection of 0.2 mg/kg of ivermectin. These camels became amicrofilaraemic 2-5 days after treatment and remained so for the length of the observation period (133 days). Treatment of two camels at the time of high microfilaraemia (06:30) resulted in adverse reaction and death.
在14只圈养骆驼（单峰驼）中的7只骆驼血液中检测到有鞘微丝蚴（平均长度278±10微米，标准误；平均宽度7.2±0.8微米）。微丝蚴血症的骆驼，无论雌雄，均食欲不振、无精打采、不愿活动且后肢无力；一些骆驼一直呈胸卧式躺卧。明显没有心脏疾病、睾丸炎和皮肤结节。微丝蚴在血液中呈现双相模式，在20:00达到峰值，在04:00至06:00之间趋于平稳。从肠系膜动脉和股动脉中发现了成虫丝虫。三只在10:00接受单次皮下注射0.2毫克/千克伊维菌素治疗的骆驼在1至2周内有明显的临床改善。这些骆驼在治疗后2至5天内变为无微丝蚴血症，并在观察期（133天）内一直保持这种状态。在微丝蚴血症高峰期（06:30）对两只骆驼进行治疗导致不良反应和死亡。
