Chantelau E, Breuer U, Leisch A C, Tanudjaja T, Reuter M
Medical Department of Nutrition and Metabolic Diseases, Heinrich-Heine-University of Düsseldorf, Germany.
Diabet Med. 1993 Apr;10(3):267-70. doi: 10.1111/j.1464-5491.1993.tb00056.x.
The impact of 'half shoes' in the treatment of neuropathic forefoot ulcers was studied in two groups of diabetic patients, who were treated either by standard treatment alone (retrospective controls, n = 22), or by standard treatment plus 'half shoes' (cases, n = 26). The groups were matched for sex, age, type, and duration of diabetes and ulcer grading. The 'half-shoe' cases' vs controls' median overall healing time was 70 vs 118 days, the median difference being 48 (95% CI: -5 to 82) days (NS). In the case group, hospitalization was required in 1/26 (4%) of patients, vs 9/22 (41%) of the control patients (chi-square, p < 0.01). The home nursing service was required in 23% of the cases vs 18% of the controls (NS). It is concluded that the use of half-shoes, in conjunction with standard treatment provided by a specialized diabetic foot clinic, may reduce the overall healing time and does reduce the hospitalization rate. This has implications for a rational strategy of treating unilateral diabetic neuropathic foot ulcers.
在两组糖尿病患者中研究了“半鞋”对神经性前足溃疡的治疗效果。一组仅接受标准治疗(回顾性对照组,n = 22),另一组接受标准治疗加“半鞋”治疗(病例组,n = 26)。两组在性别、年龄、糖尿病类型、病程和溃疡分级方面进行了匹配。“半鞋”病例组与对照组的总体愈合时间中位数分别为70天和118天,中位数差异为48天(95%可信区间:-5至82天)(无统计学意义)。病例组中1/26(4%)的患者需要住院治疗,而对照组为9/22(41%)的患者(卡方检验,p < 0.01)。病例组中23%的患者需要家庭护理服务,对照组为18%(无统计学意义)。得出的结论是,结合专业糖尿病足诊所提供的标准治疗使用半鞋,可能会缩短总体愈合时间,并确实降低了住院率。这对单侧糖尿病神经性足溃疡的合理治疗策略具有启示意义。