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[用抗坏血酸对接触钼盐工人淋巴细胞中自发及诱导的染色体畸变和姐妹染色单体交换水平的影响]

[Modification with ascorbic acid of the level of spontaneous and induced chromosome aberrations and sister chromatid exchanges in lymphocytes of workers in contact with molybdenum salts].

作者信息

Bobyleva L A, Chopikashvili L V, Alekhina N I, Zasukhina G D

出版信息

Genetika. 1993 Mar;29(3):430-4.

PMID:8486267
Abstract

Five workers of molybdenum gilding at the metallurgical works were observed prior to and after administration of ascorbic acid. Tests for chromosomal aberrations (CA) and sister chromatid exchanges (SCE) were used as the criteria for estimation. Individual sensitivity to the chemicals was revealed in the workers. Administration of ascorbic acid caused reduction of the level of chromosomal structural rearrangements.

摘要

对冶金厂的五名钼镀金工人在服用抗坏血酸前后进行了观察。使用染色体畸变(CA)和姐妹染色单体交换(SCE)测试作为评估标准。结果显示这些工人对化学物质存在个体敏感性。服用抗坏血酸导致染色体结构重排水平降低。

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