Silverman D T, Murray J L, Smart C R, Brown C C, Myers M H
Am J Surg. 1977 Mar;133(3):289-97. doi: 10.1016/0002-9610(77)90531-1.
From the End Results Group file at the National Cancer Institute, 9,745 colorectal cancer patients diagnosed from 1965 through 1971 and classified as adenocarcinoma NOS were selected to evaluate the joint effect of various prognostic factors on MST. A technic was developed which enables a physician to estimate the MST for a patient with a given set of patient/disease characteristics. The results are also summarized in an appendix, allowing the physician to bypass the calculation and refer directly to the MST. These results will aid the physician in determining whether a patient is at sufficiently high risk to warrant adjuvant therapy. The survival experience of this broad historical group of patients with varying prognostic factors can also serve as a basis for comparison of results of studies on highly selected patients treated in various experimental ways.
从美国国立癌症研究所的最终结果组文件中，选取了9745例在1965年至1971年间被诊断为结直肠癌且分类为未特指腺癌的患者，以评估各种预后因素对中位生存期（MST）的联合影响。开发了一种技术，使医生能够根据患者特定的一组患者/疾病特征来估计其MST。结果也总结在附录中，使医生无需进行计算，可直接查阅MST。这些结果将有助于医生确定患者的风险是否足够高，从而有必要进行辅助治疗。这一具有广泛预后因素的庞大历史患者群体的生存经验，也可作为比较以各种实验方式治疗的高度选择患者研究结果的基础。
