Kal'cheva E O, Shanskaia V O, Maliuta S S
Prikl Biokhim Mikrobiol. 1993 Mar-Apr;29(2):266-70.
The effect of threonine and methionine on the growth of and lysine synthesis in Streptococcus bovis st. A024/85 was studied. The character and the degree of manifestation of growth and regulation effects of these amino acids depend on their contents in the fermentation medium. The target in the regulation of lysine biosynthesis is aspartate kinase, whose synthesis is controlled by threonine and methionine. Lysine excretion was stimulated by the addition of a low concentration of dimethylsulfoxide in the medium during fermentation.
研究了苏氨酸和蛋氨酸对牛链球菌A024/85菌株生长及赖氨酸合成的影响。这些氨基酸的生长和调节作用的特征及表现程度取决于它们在发酵培养基中的含量。赖氨酸生物合成调节的靶点是天冬氨酸激酶,其合成受苏氨酸和蛋氨酸控制。在发酵过程中,培养基中添加低浓度的二甲基亚砜可刺激赖氨酸的分泌。