van Kampen M, Andreas P, Renner H
Abteilung Strahlentherapie des Klinikums Nürnberg.
Strahlenther Onkol. 1993 Apr;169(4):242-9.
In the radiotherapist's point of view lymphography and computed tomography scan compete for staging and therapy planning of testicular seminoma. We investigated whether lymphogram can be replaced by computed tomography scan. 114 patients with histologically confirmed seminoma of the testis were treated by radiotherapy at the Nürnberg Community Hospital (n = 65) and the University of Erlangen (n = 49) from 1978 through 1991. Radiological staging included both computed tomography scan and lymphography in all cases. The results of both methods were similar in 79%. Computed tomography scan led to an upstaging in 4% while lymphography was negative. 17% of the patients showed negative results considering computed tomography scan while lymphogram was positive. In accordance with these data treatment portals or doses were altered in 21%. Using the M.D. Anderson Hospital clinical staging system a stage IIa (micrometastasis < 2 cm) is not safely identified by computed tomography scan. Just lymphography can safely identify a stage IIa patient. On the other hand, lymphography shows a very high amount of false positive interpretations. However, two conclusions are made: 1. Using a conventional technic (radiation of para-aortal and ipsilateral iliac region, dose about 30 Gy HD) lymphogram can be superseded by computed tomography scan. 2. In the case of reducing treatment volume and/or dose lymphogram should be added to computed tomography scan.
在放疗科医生看来,淋巴造影和计算机断层扫描在睾丸精原细胞瘤的分期及治疗计划制定方面存在竞争关系。我们研究了淋巴造影是否可被计算机断层扫描所取代。1978年至1991年间,纽伦堡社区医院(n = 65)和埃尔朗根大学(n = 49)对114例经组织学确诊的睾丸精原细胞瘤患者进行了放射治疗。所有病例的放射学分期均包括计算机断层扫描和淋巴造影。两种方法的结果在79%的病例中相似。计算机断层扫描导致4%的病例分期上调,而淋巴造影结果为阴性。17%的患者计算机断层扫描结果为阴性,而淋巴造影结果为阳性。根据这些数据,21%的患者的治疗野或剂量发生了改变。使用MD安德森医院临床分期系统时,计算机断层扫描无法安全地识别IIa期(微转移<2 cm)患者。只有淋巴造影能够安全地识别IIa期患者。另一方面,淋巴造影显示出大量的假阳性解读。然而,可以得出两个结论:1. 使用传统技术(对腹主动脉旁和同侧髂区进行放疗,剂量约30 Gy HD)时,计算机断层扫描可取代淋巴造影。2. 在减少治疗体积和/或剂量的情况下,应在计算机断层扫描基础上增加淋巴造影。