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[淋巴造影术在精原细胞瘤中仍有意义吗?]

[Is lymphography still relevant in seminoma?].

作者信息

van Kampen M, Andreas P, Renner H

机构信息

Abteilung Strahlentherapie des Klinikums Nürnberg.

出版信息

Strahlenther Onkol. 1993 Apr;169(4):242-9.

PMID:8488460
Abstract

In the radiotherapist's point of view lymphography and computed tomography scan compete for staging and therapy planning of testicular seminoma. We investigated whether lymphogram can be replaced by computed tomography scan. 114 patients with histologically confirmed seminoma of the testis were treated by radiotherapy at the Nürnberg Community Hospital (n = 65) and the University of Erlangen (n = 49) from 1978 through 1991. Radiological staging included both computed tomography scan and lymphography in all cases. The results of both methods were similar in 79%. Computed tomography scan led to an upstaging in 4% while lymphography was negative. 17% of the patients showed negative results considering computed tomography scan while lymphogram was positive. In accordance with these data treatment portals or doses were altered in 21%. Using the M.D. Anderson Hospital clinical staging system a stage IIa (micrometastasis < 2 cm) is not safely identified by computed tomography scan. Just lymphography can safely identify a stage IIa patient. On the other hand, lymphography shows a very high amount of false positive interpretations. However, two conclusions are made: 1. Using a conventional technic (radiation of para-aortal and ipsilateral iliac region, dose about 30 Gy HD) lymphogram can be superseded by computed tomography scan. 2. In the case of reducing treatment volume and/or dose lymphogram should be added to computed tomography scan.

摘要

在放疗科医生看来,淋巴造影和计算机断层扫描在睾丸精原细胞瘤的分期及治疗计划制定方面存在竞争关系。我们研究了淋巴造影是否可被计算机断层扫描所取代。1978年至1991年间,纽伦堡社区医院(n = 65)和埃尔朗根大学(n = 49)对114例经组织学确诊的睾丸精原细胞瘤患者进行了放射治疗。所有病例的放射学分期均包括计算机断层扫描和淋巴造影。两种方法的结果在79%的病例中相似。计算机断层扫描导致4%的病例分期上调,而淋巴造影结果为阴性。17%的患者计算机断层扫描结果为阴性,而淋巴造影结果为阳性。根据这些数据,21%的患者的治疗野或剂量发生了改变。使用MD安德森医院临床分期系统时,计算机断层扫描无法安全地识别IIa期(微转移<2 cm)患者。只有淋巴造影能够安全地识别IIa期患者。另一方面,淋巴造影显示出大量的假阳性解读。然而,可以得出两个结论:1. 使用传统技术(对腹主动脉旁和同侧髂区进行放疗,剂量约30 Gy HD)时,计算机断层扫描可取代淋巴造影。2. 在减少治疗体积和/或剂量的情况下,应在计算机断层扫描基础上增加淋巴造影。

相似文献

1
[Is lymphography still relevant in seminoma?].[淋巴造影术在精原细胞瘤中仍有意义吗?]
Strahlenther Onkol. 1993 Apr;169(4):242-9.
2
Staging, treatment, and results in testicular seminoma. A 12-year report.睾丸精原细胞瘤的分期、治疗及结果。一项为期12年的报告。
Cancer. 1990 Feb 1;65(3):405-11. doi: 10.1002/1097-0142(19900201)65:3<405::aid-cncr2820650305>3.0.co;2-#.
3
Relative role of abdominal pelvic CT and lymphangiography in staging of testicular seminoma.
Urology. 1985 Aug;26(2):193-5. doi: 10.1016/0090-4295(85)90063-9.
4
Radiation therapy of testicular seminoma: a 15-year survey.睾丸精原细胞瘤的放射治疗:一项15年的调查。
Am J Clin Oncol. 1992 Feb;15(1):87-90. doi: 10.1097/00000421-199202000-00017.
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Influence of computed tomography scanning and lymphography on the management of testicular germ-cell tumours.
Clin Radiol. 1986 Nov;37(6):539-42. doi: 10.1016/s0009-9260(86)80008-3.
6
[Testicular seminoma--goal volume, dosage and technique of external radiotherapy].
Bildgebung. 1991;58 Suppl 1:53-5.
7
A review of the role of lymphography in the management of testicular tumours.淋巴造影术在睾丸肿瘤治疗中的作用综述。
Clin Radiol. 1975 Jan;26(1):89-98. doi: 10.1016/s0009-9260(75)80020-1.
8
Lymphography in retroperitoneal metastases in non-seminoma testicular tumor patients with a normal CT scan.CT扫描正常的非精原细胞瘤性睾丸肿瘤患者腹膜后转移灶的淋巴造影术。
Acta Radiol Diagn (Stockh). 1983;24(4):319-22. doi: 10.1177/028418518302400408.
9
[Comparative value of computerized tomography and lymphography in assessing the spread of the neoplastic process in testicular neoplasms].
Nowotwory. 1981 Jul-Dec;31(3-4):207-16.
10
Role of lymphangiography in staging testicular seminoma.淋巴管造影在睾丸精原细胞瘤分期中的作用。
Urology. 1991 Sep;38(3):264-6. doi: 10.1016/s0090-4295(91)80360-j.

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