Ghoniem G M, Dilworth J P, Roberts J A
Department of Urology, Tulane University School of Medicine, New Orleans.
Urology. 1993 May;41(5):484-8. doi: 10.1016/0090-4295(93)90516-d.
Nifedipine, a calcium channel blocker, was tested for its in vivo effect on the ureter and kidney during acute obstruction. There was no discernible effect on peristalsis but glomerular filtration rate was improved. Thus, nifedipine would not be expected to decrease renal colic from obstruction.
硝苯地平是一种钙通道阻滞剂,在急性梗阻期间对输尿管和肾脏的体内效应进行了测试。对蠕动没有明显影响,但肾小球滤过率有所提高。因此,预计硝苯地平不会减轻梗阻引起的肾绞痛。