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[旋毛虫病中观察到的暂时性免疫抑制:它与宿主对这种寄生虫的接受有关吗?]

[The temporary immunodepression observed in trichinosis: is it related to acceptance of this parasite by its host?].

作者信息

Faubert G

出版信息

Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):281-2.

PMID:848885
Abstract

Swiss mice given 200 Trichinella larvae followed by a further 200 larvae 21 days later were found to be immune and did not show any immunodepression to sheep red blood cells (SRBC). When the challenge dose was given 56 days after the first infection, the pattern of infection was unaffected and an immunodepression to SRBC was observed. Therefore, the immunodepression in trichinellosis might be related to the migrating phase only.

摘要

给瑞士小鼠接种200条旋毛虫幼虫,21天后再接种200条幼虫,结果发现这些小鼠具有免疫力,对绵羊红细胞(SRBC)未表现出任何免疫抑制。当在首次感染后56天给予攻击剂量时,感染模式未受影响,且观察到对SRBC的免疫抑制。因此,旋毛虫病中的免疫抑制可能仅与迁移期有关。

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