Marsh P, Wilson D J, Samples J R, Morrison J C
Casey Eye Institute, Oregon Health Sciences University, Portland, OR 97201.
Am J Ophthalmol. 1993 May 15;115(5):597-602. doi: 10.1016/s0002-9394(14)71456-4.
We studied the histopathologic changes of three eyes enucleated two weeks, eight weeks, and 17 months, respectively, after noncontact Nd:YAG cyclophotocoagulation. The histologic findings at two weeks were destruction of the nonpigmented and pigmented ciliary body epithelium, occlusion of the capillaries of the ciliary processes, and ciliary body stromal necrosis in the region of the processes. Hyperplasia of the pigmented and nonpigmented epithelium, fibrosis and near total atrophy of the ciliary processes, and partial atrophy of the ciliary muscles were present at eight weeks and 17 months. We concluded that application of treatment 1.0 to 1.5 mm posterior to the corneoscleral limbus selectively destroys the pars plicata, and that, histologically, the mechanism for reducing intraocular pressure appears to be destruction of ciliary processes with reduction of aqueous formation.
我们研究了非接触式Nd:YAG睫状体光凝术后分别于2周、8周和17个月摘除的三只眼睛的组织病理学变化。2周时的组织学表现为无色素和色素性睫状体上皮破坏、睫状突毛细血管闭塞以及突部区域的睫状体基质坏死。8周和17个月时出现色素性和无色素上皮增生、睫状突纤维化和几乎完全萎缩以及睫状肌部分萎缩。我们得出结论，在角巩膜缘后1.0至1.5毫米处进行治疗可选择性地破坏睫状突，并且从组织学上看，降低眼压的机制似乎是通过破坏睫状突减少房水生成。
