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[超声引导下腹腔神经丛阻滞术。综述与个人观察]

[The anterior sonographic-guided celiac plexus blockade. Review and personal observations].

作者信息

Zenz M, Kurz-Müller K, Strumpf M, May B

机构信息

Universitätsklinik für Anaesthesiologie, Intensiv- und Schmerztherapie, BG-Universitätsklinikum Bergmannsheil Bochum.

出版信息

Anaesthesist. 1993 Apr;42(4):246-55.

PMID:8488998
Abstract

The coeliac plexus block is an approved method for the relief of upper abdominal pain due to cancer of the upper intra-abdominal viscera or to chronic pancreatitis. While there are many reports concerning the posterior approach to the coeliac plexus block, little attention has been given the anterior approach. There are two ways of implementing the anterior approach to the coeliac plexus: CT-guided and the ultrasound guided approach. METHODS. The ultrasonic-guided anterior approach to the coeliac plexus block is used with the patient in the supine position. The aorta and discharge of the truncus coeliacus or the a. lienalis respectively, are ultrasonographically presented at two levels. After setting local cutaneous and subcutaneous anaesthesia, a 15-cm-long 25 G-needle is introduced into the epigastrium. The point of the needle is--ultrasonographically guided--inserted into the pre-aortic area near the discharge of the truncus coeliacus. The position of the needle point is ultrasonographically controlled on two levels. For the enforcement of a diagnostic coeliac plexus block after careful aspiration on two levels, 10 ml of bupivacaine 0.5% is injected. The spread of the solution is evaluated by ultrasound. If the needle position is correct; a few minutes later the patient has a feeling of warmth in the upper abdominal region. For the enforcement of a neurolytic coeliac plexus block 10 ml ethanol 96% and 10 ml prilocaine 1% can be administered. The two solutions are applied as small volumes in permanent succession. Thus the burning pain, which is often observed after the injection of alcohol, is avoided. RESULTS. In the literature there are only a few reports, about the results and side-effects after use of the anterior approach in the coeliac plexus block. The results of these investigations and our own show total pain relief or at least good pain reduction by at best 85%. The reduction in pain achieved continues in as many as 60% of the treated patients. There is the possibility to stop or at least reduce the analgesic premedication. These results are comparable with those after using the posterior approach to the coeliac plexus block. When carrying out the anterior approach in the coeliac plexus block, most of the patients showed increased intestinal motility. Therefore, about 60% of all patients had transitory diarrhoea. In 12-25% of the patients orthostatic hypotension was observed. This side-effect is avoided by an appropriate infusion before enforcement of the block. In a frequency of 4-100% the occurrence of burning pain was reported during injection of the alcohol. No serious side-effects were observed. CONCLUSIONS. The results concerning total pain relief or at least pain reduction are comparable to the posterior approach for the block. Nevertheless, there are some advantages to the ultrasound-guided anterior approach. There is less risk using this technique. No methodological complications have been observed so far. There is no risk of neurological complications such as paraplegia. Because the patients remain in the supine position, the anterior approach to the coeliac plexus block is suitable for terminally ill patients, who are not able to tolerate the prone position and need careful supervision and good ventilation. Also, no contrast medium is necessary. Only a small volume of local anaesthetics or alcohol is required. We prefer the anterior approach of the coeliac plexus block as a fast, safe and cost-effective method, which should receive increasing attention during the next few years.

摘要

腹腔神经丛阻滞是一种已获批准的缓解上腹部疼痛的方法,这些疼痛由上腹部内脏器官癌症或慢性胰腺炎引起。虽然有许多关于腹腔神经丛阻滞后路的报道,但前路却很少受到关注。实施腹腔神经丛阻滞前路有两种方法:CT引导法和超声引导法。方法:超声引导下腹腔神经丛阻滞前路法用于患者仰卧位时。在两个层面超声显示主动脉以及腹腔干或脾动脉的分支。在进行局部皮肤和皮下麻醉后,将一根15厘米长的25G针头插入上腹部。在超声引导下,将针尖插入腹腔干分支附近的主动脉前区域。在两个层面超声控制针尖位置。在仔细进行两个层面的回抽后,为实施诊断性腹腔神经丛阻滞,注射10毫升0.5%的布比卡因。通过超声评估溶液的扩散情况。如果针尖位置正确,几分钟后患者上腹部会有温热感。为实施神经破坏性腹腔神经丛阻滞,可给予10毫升96%乙醇和10毫升1%丙胺卡因。两种溶液以小剂量连续给予。这样可避免注射酒精后常出现的灼痛。结果:文献中关于腹腔神经丛阻滞前路使用后的结果和副作用的报道很少。这些研究结果以及我们自己的研究结果显示,完全缓解疼痛或至少疼痛明显减轻的比例最高可达85%。多达60%的接受治疗患者疼痛减轻得以持续。有可能停止或至少减少镇痛前用药。这些结果与腹腔神经丛阻滞后路使用后的结果相当。在进行腹腔神经丛阻滞前路时,大多数患者肠道蠕动增加。因此,约60%的患者出现短暂腹泻。12%至25%的患者出现体位性低血压。在阻滞实施前通过适当输液可避免这种副作用。在注射酒精时,有4%至100%的频率报道出现灼痛。未观察到严重副作用。结论:关于完全缓解疼痛或至少减轻疼痛的结果与后路阻滞相当。然而,超声引导下腹腔神经丛阻滞前路有一些优点。使用该技术风险较小。到目前为止未观察到方法学上的并发症。没有诸如截瘫等神经并发症的风险。因为患者保持仰卧位,腹腔神经丛阻滞前路适用于无法耐受俯卧位且需要仔细监护和良好通气的晚期患者。此外,无需造影剂。仅需要少量局部麻醉剂或酒精。我们更倾向于将腹腔神经丛阻滞前路作为一种快速、安全且经济有效的方法,在未来几年应会受到越来越多的关注。

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