Sekizuka N
Department of Obstetrics and Gynecology, Niigata University School of Medicine, Japan.
Asia Oceania J Obstet Gynaecol. 1993 Mar;19(1):13-9. doi: 10.1111/j.1447-0756.1993.tb00341.x.
The resistance index (RI) of middle cerebral artery (MCA) and umbilical artery (UA) flow velocity waveforms (FVWs) were characterized retrospectively in 60 growth-retarded fetuses in the third trimester of gestation. Reference ranges of MCA-RI, UA-RI, and the UA-RI/MCA-RI ratio to gestational age were obtained from a cross-sectional study of 150 healthy fetuses. Growth-retarded fetuses that developed fetal distress had lower MCA-RIs, higher UA-RIs, and higher UA-RI/MCA-RI ratios than growth-retarded fetuses that had good outcomes. The highest sensitivity for fetal distress was observed in the UA-RI/MCA-RI ratio (UA-RI/MCA-RI 94.1%, MCA-RI 79.4%, UA-RI 61.8%), and the highest specificity was in MCA-RI (MCA-RI 92.3%, UA-RI 84.6%, UA-RI/MCA-RI 76.9%). In growth-retarded fetuses, the combined examination of MCA FVWs and UA FVWs was more useful in assessing fetal well-being than examination of UA FVWs alone.
对60例孕晚期生长受限胎儿的大脑中动脉（MCA）和脐动脉（UA）血流速度波形（FVW）的阻力指数（RI）进行了回顾性分析。通过对150例健康胎儿的横断面研究，得出了MCA-RI、UA-RI以及UA-RI/MCA-RI比值与孕周的参考范围。发生胎儿窘迫的生长受限胎儿比结局良好的生长受限胎儿具有更低的MCA-RI、更高的UA-RI以及更高的UA-RI/MCA-RI比值。在UA-RI/MCA-RI比值中观察到对胎儿窘迫的最高敏感性（UA-RI/MCA-RI为94.1%，MCA-RI为79.4%，UA-RI为61.8%），而在MCA-RI中观察到最高特异性（MCA-RI为92.3%，UA-RI为84.6%，UA-RI/MCA-RI为76.9%）。在生长受限胎儿中，MCA FVW和UA FVW联合检查比单独检查UA FVW在评估胎儿健康状况方面更有用。
