Manabe H, Oyama C, Kitamura S, Kawashima Y
Ann Thorac Surg. 1977 Mar;23(3):245-8. doi: 10.1016/s0003-4975(10)64117-3.
Twenty-nine patients younger than 18 years of age with mitral stenosis were operated upon in the Osaka University Hospital. Five patients who underwent operation in the early period of this study died postoperatively. Follow-up study was made in 20 of the surviving patients for a period of 6 to 20 years. Three died during the follow-up period. Twelve of the survivors were in NYHA Functional Class I, 4 were in Class II, and 1 was in Class III. Reactivation of rheumatic disease did not occur after mitral valvotomy.
29名年龄小于18岁的二尖瓣狭窄患者在大阪大学医院接受了手术。在本研究早期接受手术的5名患者术后死亡。对20名存活患者进行了6至20年的随访研究。3名患者在随访期间死亡。12名存活患者处于纽约心脏协会（NYHA）心功能I级，4名处于II级，1名处于III级。二尖瓣切开术后风湿性疾病未复发。
