MacArthur C, Lewis M, Knox E G
Department of Public Health and Epidemiology, Medical School, University of Birmingham.
BMJ. 1993 Apr 3;306(6882):883-5. doi: 10.1136/bmj.306.6882.883.
To examine the association between accidental dural puncture and long term headache and related symptoms.
Postal questionnaire survey to elucidate new symptoms occurring after childbirth, and linking of these to data in obstetric and anaesthetic case notes. Women were surveyed between 13 months and nine years after delivery.
Birmingham Maternity Hospital.
4700 women who had delivered their most recent baby under epidural anaesthesia, 74 of whom had suffered an accidental dural puncture.
Frequencies of new headache or migraine or neck ache starting within three months after childbirth and lasting over six weeks.
Among the 74 women who had had an accidental dural puncture there were 17 (23%) who reported one or more of the above symptoms. By comparison, among those who had had an epidural anaesthetic but no recorded puncture, only 329 (7.1%) reported these symptoms. The duration of the headache or migraine or neck ache in the dural tap group ranged from nine weeks to over eight years. Ten of these women reported still unresolved symptoms.
Conclusions on causality were tentative. Most women would remember a dural tap, and this might influence their reporting of subsequent symptoms attributable to the event. In addition, detailed characterisation of the symptoms was not available. Nevertheless, the findings provide a clear indication of the need for further study of the possible long term sequelae of accidental dural puncture.
研究意外硬膜穿破与长期头痛及相关症状之间的关联。
通过邮寄问卷调查来阐明分娩后出现的新症状,并将这些症状与产科和麻醉科病例记录中的数据相联系。在分娩后13个月至9年之间对女性进行调查。
伯明翰妇产医院。
4700名在硬膜外麻醉下分娩其最近一个婴儿的女性,其中74名曾发生意外硬膜穿破。
产后三个月内开始且持续超过六周的新发头痛、偏头痛或颈部疼痛的发生率。
在74名发生意外硬膜穿破的女性中,有17名(23%)报告出现了上述一种或多种症状。相比之下,在接受硬膜外麻醉但无硬膜穿破记录的女性中,只有329名(7.1%)报告了这些症状。硬膜穿破组中头痛、偏头痛或颈部疼痛的持续时间从9周至8年以上不等。其中10名女性报告症状仍未缓解。
关于因果关系的结论是初步的。大多数女性会记得硬膜穿破事件,这可能会影响她们对该事件所致后续症状的报告。此外,症状的详细特征并不明确。尽管如此,这些发现明确表明有必要进一步研究意外硬膜穿破可能的长期后遗症。