Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, China.
Department of Anesthesiology, Yale University School of Medicine, 20 York Street, New Haven, CT, 06510, USA.
Curr Pain Headache Rep. 2022 Jun;26(6):441-452. doi: 10.1007/s11916-022-01041-x. Epub 2022 Mar 30.
This manuscript aims to review the risks and the current treatments for postdural puncture headache (PDPH).
PDPH is a relatively frequent complication after neuraxial blocks. It is typically orthostatic in nature, presenting as a positional and dull aching or throbbing headache, with added dysregulation of auditory and/or visual signals. Certain characteristics, such as female sex and young age, may predispose patients to the development of PDPH, as may factors such as previous PDPH, bearing down during the second stage of labor, and the neuraxial technique itself. Long-term complications including chronic headache for years following dural puncture have brought into question of the historical classification of PDPH as a self-limiting headache. So far, the underlying mechanism governing PDPH remains under investigation, while a wide variety of prophylactic and therapeutic measures have been explored with various degree of success. In case of mild PDPH, conservative management involving bed rest and pharmacological management should be used as first-line treatment. Nerve blocks are highly efficient alternatives for PDPH patients who do not respond well to conservative treatment. In case of moderate-to-severe PDPH, epidural blood patch remains the therapy of choice. An interdisciplinary approach to care for patients with PDPH is recommended to achieve optimal outcomes.
本文旨在综述硬脊膜穿破后头痛(PDPH)的风险和当前治疗方法。
PDPH 是椎管内阻滞后相对常见的并发症。其通常为直立性头痛,表现为位置性和钝痛或搏动性头痛,伴有听觉和/或视觉信号失调。某些特征,如女性和年轻,可能使患者容易发生 PDPH,如既往 PDPH、第二产程屏气用力,以及椎管内技术本身。硬膜穿刺后数年的长期并发症,包括慢性头痛,使得 PDPH 作为一种自限性头痛的历史分类受到质疑。迄今为止,PDPH 的发病机制仍在研究中,同时也探索了多种预防和治疗措施,取得了不同程度的成功。对于轻度 PDPH,应采用卧床休息和药物治疗等保守治疗作为一线治疗。神经阻滞是对保守治疗反应不佳的 PDPH 患者的有效替代治疗方法。对于中重度 PDPH,硬膜外血贴仍然是首选的治疗方法。建议采用多学科方法治疗 PDPH 患者,以获得最佳效果。