石棉相关的家族性间皮瘤

Asbestos-related familial mesothelioma.

作者信息

Bianchi C, Brollo A, Zuch C

机构信息

Laboratory of Pathological Anatomy, Hospital of Monfalcone, Italy.

出版信息

Eur J Cancer Prev. 1993 May;2(3):247-50. doi: 10.1097/00008469-199305000-00009.

DOI:10.1097/00008469-199305000-00009

PMID:8490544

Abstract

Familial mesotheliomas are reported in four pairs of patients. The group includes six men and two women, aged between 44 and 84 years. A blood relation (father-son) existed in two pairs only. All the present patients had histories of exposure to asbestos; in five cases exposure had occurred in the shipyards. Familial mesothelioma could represent a useful model for investigating genetic-environmental interactions.

摘要

据报道，有四对患者患有家族性间皮瘤。该组包括6名男性和2名女性，年龄在44岁至84岁之间。只有两对存在血缘关系（父子）。所有现有患者都有接触石棉的病史；其中5例是在造船厂接触的。家族性间皮瘤可能是研究基因与环境相互作用的有用模型。