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使用呼气氢测量法评估猫甲状腺功能亢进治疗前后的口盲肠转运时间。

Use of breath hydrogen measurement to evaluate orocecal transit time in cats before and after treatment for hyperthyroidism.

作者信息

Schlesinger D P, Rubin S I, Papich M G, Hamilton D L

机构信息

Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon.

出版信息

Can J Vet Res. 1993 Apr;57(2):89-94.

Abstract

Orocecal transit time was evaluated in 13 cats diagnosed with hyperthyroidism. Transit was determined by measuring the change in breath hydrogen and methane concentrations following oral administration of a nonabsorbable carbohydrate (lactulose). Transit times before and three to four weeks after treatment of the hyperthyroidism with radioactive iodine were compared. There was a significant prolongation of transit time, as determined by a change in hydrogen concentration, following correction of the hyperthyroidism (p = 0.034). Average transit times and standard errors were 27.7 +/- 3.7 minutes before treatment and 56.5 +/- 12.1 minutes after treatment. Methane was not detected in any of the samples. Hyperthyroidism appears to be associated with an accelerated small intestinal transit time in cats.

摘要

对13只被诊断为甲状腺功能亢进的猫进行了口盲肠转运时间评估。通过测量口服不可吸收碳水化合物(乳果糖)后呼出气体中氢气和甲烷浓度的变化来确定转运情况。比较了用放射性碘治疗甲状腺功能亢进之前以及治疗后三到四周的转运时间。甲状腺功能亢进得到纠正后,由氢气浓度变化确定的转运时间显著延长(p = 0.034)。治疗前平均转运时间和标准误为27.7 +/- 3.7分钟,治疗后为56.5 +/- 12.1分钟。所有样本中均未检测到甲烷。甲状腺功能亢进似乎与猫小肠转运时间加快有关。

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Bentiromide:xylose test in healthy cats.
Am J Vet Res. 1982 Dec;43(12):2272-3.
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Feline hyperthyroidism.
Vet Clin North Am Small Anim Pract. 1984 Jul;14(4):809-26. doi: 10.1016/s0195-5616(84)50082-5.
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Production and excretion of hydrogen gas in man.人体中氢气的产生与排泄
N Engl J Med. 1969 Jul 17;281(3):122-7. doi: 10.1056/NEJM196907172810303.
9
Thyroid hormones and the gut.甲状腺激素与肠道
Gut. 1971 Feb;12(2):172-7. doi: 10.1136/gut.12.2.172.

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