Tashiro T, Todo K, Haruta Y, Tanaka K, Nagata M, Nakamura M, Yamamoto K, Yoshitake T, Miyahara Y
Department of Thoracic and Cardiovascular Surgery, St Mary's Hospital, Kurume, Japan.
Kyobu Geka. 1993 May;46(5):385-90.
As the indications for coronary artery bypass grafting (CABG) among patients with poor left ventricular function remain incompletely defined, We undertook the study to assess the results of CABG surgery for a group of such patients. We retrospectively reviewed the clinical features and outcome for 7 patients with poor left ventricular function defined as an ejection fraction below 0.3 who underwent CABG. The mean age of the patients was 63 years (range, 38 to 78 years), and 4 were 70 years of age or older. All patients had history of previous myocardial infarction, and all had left main trunk stenosis or left main equivalent stenosis. The patients underwent CABG with three to six distal anastomoses (mean, 4.3/patient), the internal thoracic artery could be used in all patients, for one or two distal anastomoses (mean, 1.6/patient). Combined coronary endarterectomy was performed in 2 patients. With the exception of one 78-year-old patient with renal failure who died during the early postoperative period, all patients showed marked postoperative improvement in cardiac function. Cardiac catheterization and exercise stress test studies revealed significant improvement in left ventricular function and exercise tolerance in these six patients. These results suggest that excellent results can be obtained with CABG surgery in patients with poor left ventricular function when the viability of the myocardium in the bypassed area has been confirmed.
由于左心室功能不佳患者进行冠状动脉旁路移植术(CABG)的指征仍未完全明确,我们开展了这项研究,以评估一组此类患者接受CABG手术的结果。我们回顾性分析了7例左心室功能不佳(定义为射血分数低于0.3)且接受CABG手术患者的临床特征和结局。患者的平均年龄为63岁(范围38至78岁),其中4例年龄在70岁及以上。所有患者均有既往心肌梗死病史,且均有左主干狭窄或等同左主干狭窄。患者接受了3至6个远端吻合的CABG手术(平均每位患者4.3个),所有患者均可使用胸廓内动脉进行1或2个远端吻合(平均每位患者1.6个)。2例患者进行了联合冠状动脉内膜切除术。除1例78岁合并肾衰竭的患者术后早期死亡外,所有患者术后心脏功能均有显著改善。心脏导管检查和运动负荷试验研究显示,这6例患者的左心室功能和运动耐量有显著改善。这些结果表明,当旁路区域心肌的存活性得到证实时,左心室功能不佳的患者接受CABG手术可取得良好效果。