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[法国吉伦特省痴呆症患病率]

[Prevalence of dementia in Gironde (France)].

作者信息

Letenneur L, Dequae L, Jacqmin H, Nuissier J, Decamps A, Barberger-Gateau P, Commenges D, Dartigues J F

机构信息

Unité INSERM U330, Université de Bordeaux II.

出版信息

Rev Epidemiol Sante Publique. 1993;41(2):139-45.

PMID:8493392
Abstract

The objective of the study is to estimate the prevalence of dementia using the data of the Paquid cohort. A sample of 3,149 subjects aged 65 years and older living at home or in institution was randomly chosen in Gironde (France). A questionnaire and psychometric tests were used to evaluate cognitive functioning and the presence of dementia was assessed through DSM III Diagnostic and Statistical Manual of mental disorders (ed. III) criteria. Hachinski scale and work group NINCDS-ADRDA criteria were applied to confirm the presence of dementia and identify Alzheimer's disease. Overall prevalence was estimated to 4.3%. No difference was found between men and women. The prevalence increased with age with nearly a doubling every 5 years of age. In institution, dementia frequency remained stable. The relative risk of a demented subject to be institutionalized with regard to a non demented subject decreased with age.

摘要

该研究的目的是利用帕基德队列的数据估算痴呆症的患病率。在法国吉伦特省,随机选取了3149名年龄在65岁及以上、居住在家中或机构中的受试者作为样本。使用一份问卷和心理测量测试来评估认知功能,并通过《精神疾病诊断与统计手册》第三版(DSM III)标准评估痴呆症的存在情况。应用哈金斯基量表和美国国立神经疾病与中风研究所-阿尔茨海默病及相关疾病协会(NINCDS-ADRDA)工作组标准来确认痴呆症的存在并识别阿尔茨海默病。总体患病率估计为4.3%。男性和女性之间未发现差异。患病率随年龄增长而增加,每5岁年龄患病率几乎翻倍。在机构中,痴呆症的发病率保持稳定。与非痴呆症受试者相比,痴呆症患者被送入机构的相对风险随年龄降低。

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