细菌细胞表面蛋白的分子进化

Molecular evolution of bacterial cell-surface proteins.

作者信息

Goward C R, Scawen M D, Murphy J P, Atkinson T

机构信息

Division of Biotechnology, PHLS Centre for Applied Microbiology and Research, Porton Down, Salisbury, UK.

出版信息

Trends Biochem Sci. 1993 Apr;18(4):136-40. doi: 10.1016/0968-0004(93)90021-e.

DOI:10.1016/0968-0004(93)90021-e

PMID:8493725

Abstract

The cell-surface proteins of the infective bacteria Streptococcus and Staphylococcus are probably involved in the process of infection. These proteins share many features including secretion signal peptides, cell-wall spanning regions, membrane anchor domains and repeated domains of various functions. These common features may have evolved by gene duplication and swapping of gene fragments.

摘要

感染性细菌链球菌和葡萄球菌的细胞表面蛋白可能参与感染过程。这些蛋白具有许多共同特征，包括分泌信号肽、跨细胞壁区域、膜锚定结构域和具有各种功能的重复结构域。这些共同特征可能是通过基因复制和基因片段交换进化而来的。