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Method for sequential staining of GTL-banded metaphases with fluorescent-labeled chromosome-specific paint probes.

作者信息

Jalal S M, Law M E, Christensen E R, Spurbeck J L, Dewald G W

机构信息

Section of Laboratory Genetics, Mayo Clinic, Rochester, Minnesota 55905.

出版信息

Am J Med Genet. 1993 Apr 1;46(1):98-103. doi: 10.1002/ajmg.1320460117.

Abstract

We describe a method for use of fluorescent-labeled whole chromosome-specific paint probes on GTL-banded metaphases to utilize the combined potential of these techniques for defining chromosome abnormalities. The efficacy of this method was tested on 6 cases involving different chromosome abnormalities and various tissues, including blood, amniotic fluid, skin fibroblasts, and bone marrow.

摘要

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