Jalal S M, Law M E, Christensen E R, Spurbeck J L, Dewald G W
Section of Laboratory Genetics, Mayo Clinic, Rochester, Minnesota 55905.
Am J Med Genet. 1993 Apr 1;46(1):98-103. doi: 10.1002/ajmg.1320460117.
We describe a method for use of fluorescent-labeled whole chromosome-specific paint probes on GTL-banded metaphases to utilize the combined potential of these techniques for defining chromosome abnormalities. The efficacy of this method was tested on 6 cases involving different chromosome abnormalities and various tissues, including blood, amniotic fluid, skin fibroblasts, and bone marrow.