Schreiber J, Mann W, Lieb W
Hals-Nasen-Ohren-Klinik, Universität Mainz.
Laryngorhinootologie. 1993 Apr;72(4):187-92. doi: 10.1055/s-2007-997882.
The objective of this study was to find additional sonomorphological criteria for determining the status of enlarged lymph nodes. By using colour-coded duplex sonography the perfusion of 63 lymph nodes in the neck was analysed. The status was confirmed either histologically or clinically (29 metastases from squamous cell carcinomas and 34 acute or chronic inflammatory nodal diseases). A quantitative evaluation of the pulsatility measured in 51 lymph nodes by computing the Pourcelot-Ratio and the Mean Pulsatility Index yielded significant differences between the two groups. By definition of a limiting value of the Pourcelot-Ratio (0.75) for the prediction of benignity, the specificity and the accuracy in screening for metastases were improved as compared to clinical examination and B-mode sonography. Additional criteria of dignity were found by qualitative evaluation of nodal perfusion patterns (presence and distribution of perfusion, partial loss of perfusion). The use of colour-coded duplex sonography in nodal disease of the neck provides an improvement of early and noninvasive diagnosis of regional metastatic involvement.
本研究的目的是寻找用于确定肿大淋巴结状态的额外超声形态学标准。通过使用彩色编码双功超声对63个颈部淋巴结的灌注情况进行分析。其状态通过组织学或临床检查得以确认（29例鳞状细胞癌转移以及34例急慢性炎性淋巴结疾病）。通过计算普尔塞尔洛比值（Pourcelot-Ratio）和平均搏动指数对51个淋巴结的搏动性进行定量评估，结果显示两组之间存在显著差异。通过定义普尔塞尔洛比值的一个极限值（0.75）来预测良性，与临床检查和B型超声相比，转移筛查的特异性和准确性得到了提高。通过对淋巴结灌注模式进行定性评估（灌注的存在与分布、灌注的部分丧失）发现了额外的鉴别标准。彩色编码双功超声在颈部淋巴结疾病中的应用提高了区域转移累及的早期无创诊断水平。
