3-三氮烯基吡咯：合成与抗肿瘤活性
3-Triazenopyrroles: synthesis and antineoplastic activity.
作者信息
Dattolo G, Cirrincione G, Almerico A M, Aiello E, Grimaudo S, Diana P, Rausa L, Dusonchet L, Crosta L, Tolomeo M
机构信息
Istituto Farmacochimico, Facoltà di Farmacia, Università degli Studi di Palermo.
出版信息
Farmaco. 1993 Feb;48(2):191-4.
PMID:8494597
Abstract
Some 3-triazenopyrroles were prepared by coupling 3-diazopyrroles and secondary amines. In preliminary in vitro screening tests derivatives 3 showed to be cytotoxic and exhibited mutagenic effects.
摘要
通过3-重氮吡咯与仲胺偶联制备了一些3-三氮烯基吡咯。在初步的体外筛选试验中，衍生物3显示出细胞毒性并具有诱变作用。
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