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体外受精程序中多胎妊娠的预防

Prevention of multiple pregnancies in an in vitro fertilization program.

作者信息

Nijs M, Geerts L, van Roosendaal E, Segal-Bertin G, Vanderzwalmen P, Schoysman R

机构信息

Vitro Fertilization Laboratory, Van Helmont Ziekenhuis, Vilvoorde, Belgium.

出版信息

Fertil Steril. 1993 Jun;59(6):1245-50. doi: 10.1016/s0015-0282(16)55984-6.

Abstract

OBJECTIVE

To limit the high number of multiple pregnancies in an IVF program.

SETTING

In Vitro Fertilization Laboratory, Fertility Department, Public Hospital.

INTERVENTIONS

The number of embryos transferred was limited to two instead of three.

RESULTS

Limiting the number of embryos transferred to only two did not influence the take home baby rate but eliminated triplet and quadruplet gestations. Moreover, the number of patients with good quality supernumerary embryos available for cryopreservation increased.

CONCLUSIONS

To reduce the high frequency of multiple gestations in an IVF program, the number of embryos replaced should be limited to a maximum of two.

摘要

目的

限制体外受精(IVF)项目中多胎妊娠的高发生率。

地点

公立医院生殖科体外受精实验室。

干预措施

将移植胚胎数量限制为两个而非三个。

结果

将移植胚胎数量限制为仅两个并未影响活产率,但消除了三胎和四胎妊娠。此外,可用于冷冻保存的优质多余胚胎的患者数量增加。

结论

为降低体外受精项目中多胎妊娠的高发生率,移植胚胎数量应限制在最多两个。

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