移植两个而非三个胚胎以降低多胎妊娠风险：一项回顾性分析
The transfer of two embryos instead of three to reduce the risk of multiple pregnancy: a retrospective analysis.
作者信息
Matson P L, Browne J, Deakin R, Bellinge B
机构信息
Concept Fertility Centre, King Edward Memorial Hospital, Subiaco, Australia.
出版信息
J Assist Reprod Genet. 1999 Jan;16(1):1-5. doi: 10.1023/a:1022581225987.
PURPOSE
Our purpose was to investigate whether a reduction in the number of embryos transferred from three to two would help reduce the incidence of multiple pregnancies and yet leave the pregnancy rate unaffected.
METHODS
Women were treated in a routine clinical in vitro fertilization program and the results analyzed retrospectively.
RESULTS
There was no reduction in the pregnancy rate when two embryos were transferred compared with three. Indeed, there was actually an increase in pregnancy rate after the transfer of two embryos in those cases with one or more embryos remaining after the transfer.
CONCLUSIONS
The transfer of only two embryos compared to three in women younger than 40 years of age does not compromise the chance of pregnancy. Triplets were not seen in the limited series of patients when only two embryos were transferred, but the incidence of twins remained the same. Further consideration should be given to strategies that enable the transfer of single embryos without compromising the pregnancy rate.
目的
我们的目的是研究将移植胚胎数量从三个减少到两个是否有助于降低多胎妊娠的发生率，同时不影响妊娠率。
方法
对在常规临床体外受精项目中接受治疗的女性进行回顾性结果分析。
结果
与移植三个胚胎相比，移植两个胚胎时妊娠率没有降低。实际上，在移植后仍有一个或多个胚胎留存的情况下，移植两个胚胎后的妊娠率反而有所增加。
结论
对于40岁以下的女性，与移植三个胚胎相比，仅移植两个胚胎不会降低妊娠几率。在仅移植两个胚胎的有限患者系列中未出现三胎，但双胎发生率保持不变。应进一步考虑在不降低妊娠率的情况下能够移植单个胚胎的策略。
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