Brewerton D A, Cockburn C, James D C, James D G, Neville E
Clin Exp Immunol. 1977 Feb;27(2):227-9.
The HLA antigens were identified in sixty-five patients with sarcoidosis, comprising forty-five with uveitis, twelve with erythema nodosum and eight with arthritis. In the group with arthritis, B8 was present in seven of eight (P = 0-0016) and the haplotype 1,8 in five of eight (P = 0-0053). A1 was present in 44% with uveitis (P = 0-04). There was no other significant disturbance of antigen frequencies in uveitis or in erythema nodosum, but it was noteworthy that B27 was present in only two patients with uveitis.
在65例结节病患者中鉴定出HLA抗原，其中45例患有葡萄膜炎，12例患有结节性红斑，8例患有关节炎。在关节炎组中，8例中有7例存在B8（P = 0.0016），8例中有5例存在单倍型1,8（P = 0.0053）。44%的葡萄膜炎患者存在A1（P = 0.04）。葡萄膜炎或结节性红斑患者的抗原频率没有其他显著异常，但值得注意的是，只有2例葡萄膜炎患者存在B27。
