[阻塞性睡眠呼吸暂停综合征在未使用和使用持续气道正压通气（CPAP）治疗时的连续无创血压测量]

[Continuous noninvasive blood pressure measurement in obstructive sleep apnea syndrome without and with CPAP therapy].

作者信息

Kellner C, Kirchheiner T, Rühle K H

机构信息

Klinik Ambrock, Zentrum für Pneumologie und Thoraxchirurgie, Hagen.

出版信息

Pneumologie. 1993 Mar;47 Suppl 1:178-80.

PMID:8497475

Abstract

The obstructive sleep apnea syndrome is accompanied with episodic increases of systemic blood pressure (B.P.) and possibly with persistent hypertension. to find out the influence of nCPAP therapy on systemic blood pressure in sleep apnea patients, 10 patients (apnea index 9-51/h) were monitored by means of continuous noninvasive blood pressure measurement during polygraphy, circulation was examined before and 2-7 days after CPAP therapy. Every 30 minutes a 2-minute period of the systolic and diastolic B.P. was visually averaged and from these data the mean pressure of 7 hours nocturnal sleep was calculated. The mean systolic pressure before therapy was 139 +/- 32 mmHg and decreased to 122 +/- 14 mmHg under nCPAP (significant), the mean diastolic pressure before therapy was 74 +/- 17 mmHg and decreased to 64 +/- 8 mmHg under nCPAP. The maximal B.P. during the 7-hour measurement decreased from 155 +/- 27 mmHg to 137 +/- 20 mmHg under nCPAP.

摘要

阻塞性睡眠呼吸暂停综合征伴有系统性血压（B.P.）的间歇性升高，可能还伴有持续性高血压。为了探究持续气道正压通气（nCPAP）治疗对睡眠呼吸暂停患者系统性血压的影响，在多导睡眠监测期间，通过连续无创血压测量对10例患者（呼吸暂停指数为9 - 51次/小时）进行监测，并在CPAP治疗前及治疗后2 - 7天检查循环情况。每30分钟对2分钟的收缩压和舒张压进行目测平均，并根据这些数据计算7小时夜间睡眠的平均血压。治疗前平均收缩压为139±32 mmHg，在nCPAP治疗下降至122±14 mmHg（差异显著），治疗前平均舒张压为74±17 mmHg，在nCPAP治疗下降至64±8 mmHg。在7小时测量期间，最大血压在nCPAP治疗下从155±27 mmHg降至137±20 mmHg。