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使用长血管成形术球囊导管治疗冠状动脉长段狭窄。

Treatment of long coronary artery narrowings with long angioplasty balloon catheters.

作者信息

Tenaglia A N, Zidar J P, Jackman J D, Fortin D F, Krucoff M W, Tcheng J E, Phillips H R, Stack R S

机构信息

Department of Medicine, Duke University Medical Center, Durham, North Carolina.

出版信息

Am J Cardiol. 1993 Jun 1;71(15):1274-7. doi: 10.1016/0002-9149(93)90539-o.

Abstract

Balloon angioplasty of long coronary artery narrowings has been associated with a lower rate of acute success, and a higher rate of acute complications and restenosis than that observed for short narrowings. Angioplasty catheters with longer length balloons (30 and 40 mm) are now available, and the objective of this study was to determine the acute and long-term success for patients with long coronary artery narrowings treated with these longer balloons. All patients with long narrowings (> or = 10 mm) treated with long balloons at 1 institution over a 1-year period were identified (93 narrowings in 89 patients), and acute and long-term outcomes were carefully documented. Procedural success (residual stenosis < or = 50%) was 97%. Abrupt closure occurred in 6% and major dissection in 11% of narrowings. Clinical success (procedural success without in-hospital death, bypass surgery or myocardial infarction) was achieved in 90% of patients. Repeat catheterization was performed in 61 patients (76% of those eligible), and restenosis was found in 50 to 55%, depending on the definition used. The treatment of long coronary artery narrowings using angioplasty catheters with longer balloons leads to high rates of acute success. However, there is a high rate of restenosis. New interventional devices for long lesions should be compared with long balloons in a randomized controlled trial.

摘要

与短冠状动脉狭窄相比,长冠状动脉狭窄的球囊血管成形术急性成功率较低,急性并发症和再狭窄发生率较高。现在已有长度更长的球囊(30和40毫米)的血管成形术导管,本研究的目的是确定使用这些更长球囊治疗长冠状动脉狭窄患者的急性和长期成功率。在1年期间,确定了在1家机构接受长球囊治疗的所有长狭窄(≥10毫米)患者(89例患者中的93处狭窄),并仔细记录了急性和长期结果。手术成功率(残余狭窄≤50%)为97%。6%的狭窄发生急性闭塞,11%发生严重夹层。90%的患者获得临床成功(手术成功且无院内死亡、搭桥手术或心肌梗死)。61例患者(占 eligible患者的76%)进行了重复导管插入术,根据所使用的定义,再狭窄发生率为50%至55%。使用带有更长球囊的血管成形术导管治疗长冠状动脉狭窄可获得较高的急性成功率。然而,再狭窄发生率较高。在随机对照试验中,应将用于长病变的新型介入装置与长球囊进行比较。

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