Irwin P P, Hammonds W D, Galloway N T
Department of Surgery, Emory University School of Medicine, Atlanta.
Br J Urol. 1993 Apr;71(4):413-6. doi: 10.1111/j.1464-410x.1993.tb15983.x.
Thirteen patients with interstitial cystitis (IC), whose predominant symptom was pelvic or urethral pain, were treated with a series of lumbar epidural local anaesthetic blocks over an 18-month period. Response was evaluated by interview and with voiding diaries and visual analogue scales (VAS) for pain. Of the 55 injections given, immediate pain relief (lasting longer than 24 h) was obtained from 41 (75%). The duration of subsequent pain relief varied considerably, ranging from 2 to 75 days (mean 15.1). Pain relief was accompanied by significant improvement in sleep habit and quality of life. A good correlation was noted between verbally expressed pain and the recorded VAS pain scores. Urinary frequency and average voided volumes were unaffected by treatment. Two patients failed to obtain any relief. Apart from minor transient backache at the injection site, there were no complications from the procedure. Lumbar sympathetic epidural blockade is an excellent means of providing pain relief in interstitial cystitis.
13例间质性膀胱炎(IC)患者,其主要症状为盆腔或尿道疼痛,在18个月期间接受了一系列腰椎硬膜外局部麻醉阻滞治疗。通过访谈、排尿日记和疼痛视觉模拟量表(VAS)对疗效进行评估。在55次注射中,41次(75%)获得了即时疼痛缓解(持续超过24小时)。随后疼痛缓解的持续时间差异很大,从2天到75天不等(平均15.1天)。疼痛缓解伴随着睡眠习惯和生活质量的显著改善。口头表达的疼痛与记录的VAS疼痛评分之间存在良好的相关性。尿频和平均排尿量不受治疗影响。2例患者未获得任何缓解。除注射部位轻微短暂的背痛外,该操作无并发症。腰椎交感神经硬膜外阻滞是间质性膀胱炎疼痛缓解的一种极佳方法。