两种抗脑膜炎奈瑟菌人单克隆抗体可变区基因的序列测定
Sequence determination of variable region genes of two human monoclonal antibodies against Neisseria meningitidis.
作者信息
Ayala Avila M, Vazques J, Danielsson L, Fernández de Cossío M E, Borrebaeck C A
机构信息
Department of Immunotechnology, Lund University, Sweden.
出版信息
Gene. 1993 May 30;127(2):273-4. doi: 10.1016/0378-1119(93)90734-k.
PMID:8500770
Abstract
Nucleotide sequences for the variable regions of both the heavy and light chains for two human monoclonal antibodies have been determined. Both antibodies are directed against an outer membrane protein of Neisseria meningitidis, and their genes show a low resemblance to germline sequences.
摘要
已确定两种人类单克隆抗体重链和轻链可变区的核苷酸序列。这两种抗体均针对脑膜炎奈瑟菌的一种外膜蛋白，且它们的基因与种系序列的相似性较低。
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