Jamal S A, Solomon L D
Jewish General Hospital, McGill University, Quebec, Canada.
J Cataract Refract Surg. 1993 May;19(3):333-8. doi: 10.1016/s0886-3350(13)80301-x.
We retrospectively reviewed 542 consecutive cases of extracapsular cataract extraction with implantation of a plano-convex laser ridge posterior chamber intraocular lens. We were interested in the incidence and probability of the development of postcapsular epithelial pearling that required laser capsulotomy and the risk factors associated with it. After four years of follow-up, 21% of all cases had developed pearling. Over the same period, the probability of pearling, as determined by the Kaplan-Meier curves, was 29% with a 95% confidence interval between 22% and 36%. After one year of follow-up, the probability of pearling was 5%; after two years, 15%; after three years, 24%. Younger age (50 years or less), larger optic, and smaller IOL were identified as significant risk factors when each of these factors was analyzed separately. When all risk factors were studied together, and after applying confounding statistics, only younger age was identified as a significant risk factor (P = .003).
我们回顾性研究了542例连续性的囊外白内障摘除术联合植入平凸型激光嵴后房型人工晶状体的病例。我们关注需要激光切开后囊的后囊上皮珠样化的发生率和发生概率，以及与之相关的危险因素。经过四年的随访，所有病例中有21%出现了珠样化。在同一时期，根据Kaplan-Meier曲线确定的珠样化概率为29%，95%置信区间在22%至36%之间。随访一年后，珠样化概率为5%；两年后为15%；三年后为24%。当分别分析每个因素时，年龄较小（50岁及以下）、光学部较大和人工晶状体较小被确定为显著危险因素。当综合研究所有危险因素并应用混杂统计学方法后，只有年龄较小被确定为显著危险因素（P = .003）。
