青少年皮肌炎中的人类白细胞抗原II类等位基因
HLA class II alleles in juvenile dermatomyositis.
作者信息
Vavrincová P, Havelka S, Cerna M, Stastny P
机构信息
Pediatric Rheumatology Unit, Institute of Rheumatology, Prague, Czech Republic.
出版信息
J Rheumatol Suppl. 1993 Apr;37:17-8.
PMID:8501745
Abstract
HLA class II alleles were investigated in 27 Czech patients (11 females and 16 males) with juvenile dermatomyositis. The immunogenetic investigation comprised determination of DRB1, DRB3, DRB5, DQA1, DQB1, and DPB1 alleles. Their prevalence was compared with that found in healthy Czech controls. No allele was found significantly more frequently in patients than in controls.
摘要
对27名患有青少年皮肌炎的捷克患者（11名女性和16名男性）的HLA II类等位基因进行了研究。免疫遗传学研究包括对DRB1、DRB3、DRB5、DQA1、DQB1和DPB1等位基因的测定。将它们的患病率与捷克健康对照者中的患病率进行了比较。未发现患者中任何等位基因的出现频率显著高于对照者。
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